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A small number of people with cystic fibrosis have a certain changed (mutated) gene called the G551D mutation.

If you have this changed gene and you are age 6 or older, the medicine ivacaftor (Kalydeco) can target the genetic cause of your lung problems and may help improve lung function.

The initial decision to take drugs is voluntary for most people, but repeated drug use can lead to brain changes that challenge an addicted person’s self-control and interfere with their ability to resist intense urges to take drugs.

For more than a century Folsom and San Quentin were the end of the line in California's penal system; they were the state's only maximum-security penitentiaries.

During the early 1980s, as California's inmate population began to climb, Folsom became dangerously overcrowded.

From 1984 to 1994 California built eight new maximum-security (Level 4) facilities.

The bullet holes in the ceilings of Folsom's cellblocks, left by warning shots, are the last traces of the prison's violent years.

Trump has added his voice to those condemning last night's bomb attack in Manchester.

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